From the train station: Please take S-Bahn no. S5 (direction Westkreuz), S3 or S75 (direction Spandau) and get off at the stop Zoologischer Garten. Change to underground/subway U9 (direction Osloer Straße) and get off at the stop Birkenstraße. The hotel is about 100 m away.
From the airport:
From Tegel airport: Your best choice is bus TXL (direction S+U Alexanderplatz). Get off at the stop Turmstraße and Change to bus M27 (direction S+U Pankow) and get off at the stop Havelbergstraße. From there it is a short walk of around 5 minutes to the Mercure Hotel MOA Berlin.
From Schönefeld airport: The best way is to take the express train ( S-Bahn) or the regional train (Regional Express) to Zoologischer Garten. From Zoologischer Garten you take the U9 (subway) in direction Osloer Str. Please leave the U9 at the Station Birkenstr. From there its just 200 metres to the Hotel.
Schedules for the public transport of Berlin can be found here.
By car: The MOA offers 550 parking spaces for reasonable prices and direct entrance to the hotel. The car park is part of the shopping centre "MOA Bogen", please enter Birkenstrasse 21 into your GPS. After the entrance barrier turn left, at the top deck you will find the direct entry to the hotel reception.